The Making of a CYP3A Biomarker Panel for Guiding Drug Therapy
نویسندگان
چکیده
منابع مشابه
The Making of a CYP3A Biomarker Panel for Guiding Drug Therapy
CYP3A ranks among the most abundant cytochrome P450 enzymes in the liver, playing a dominant role in metabolic elimination of clinically used drugs. A main member in CYP3A family, CYP3A4 expression and activity vary considerably among individuals, attributable to genetic and non-genetic factors, affecting drug dosage and efficacy. However, the extent of genetic influence has remained unclear. T...
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ژورنال
عنوان ژورنال: Journal of Personalized Medicine
سال: 2012
ISSN: 2075-4426
DOI: 10.3390/jpm2040175